Pemphigus autoimmunity: Hypotheses and realities
نویسندگان
چکیده
منابع مشابه
Pemphigus autoimmunity: Hypotheses and realities
The goal of contemporary research in pemphigus vulgaris and pemphigus foliaceus is to achieve and maintain clinical remission without corticosteroids. Recent advances of knowledge on pemphigus autoimmunity scrutinize old dogmas, resolve controversies, and open novel perspectives for treatment. Elucidation of intimate mechanisms of keratinocyte detachment and death in pemphigus has challenged th...
متن کاملSex hormones, glucocorticoids and autoimmunity: facts and hypotheses
Increasing knowledge on the regulation of immune responses over the past decade has made it clear that the immune system is involved in complex interactions with most, if not all, of the biological systems responsible for normal homeostasis. The evidence for important interplays between the immune and endocrine systems has launched the whole new field of neuroimmunoendocrinology which has attra...
متن کاملSex hormones, glucocorticoids and autoimmunity: facts and hypotheses.
Increasing knowledge on the regulation of immune responses over the past decade has made it clear that the immune system is involved in complex interactions with most, if not all, of the biological systems responsible for normal homeostasis. The evidence for important interplays between the immune and endocrine systems has launched the whole new field of neuroimmunoendocrinology which has attra...
متن کاملp38 MAPK Signaling in Pemphigus: Implications for Skin Autoimmunity
p38 mitogen activated protein kinase (p38 MAPK) signaling plays a major role in the modulation of immune-mediated inflammatory responses and therefore has been linked with several autoimmune diseases. The extent of the involvement of p38 MAPK in the pathogenesis of autoimmune blistering diseases has started to emerge, but whether it pays a critical role is a matter of debate. The activity of p3...
متن کاملNon-classical forms of pemphigus: pemphigus herpetiformis, IgA pemphigus, paraneoplastic pemphigus and IgG/IgA pemphigus*
The pemphigus group comprises the autoimmune intraepidermal blistering diseases classically divided into two major types: pemphigus vulgaris and pemphigus foliaceous. Pemphigus herpetiformis, IgA pemphigus, paraneoplastic pemphigus and IgG/IgA pemphigus are rarer forms that present some clinical, histological and immunopathological characteristics that are different from the classical types. Th...
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ژورنال
عنوان ژورنال: Autoimmunity
سال: 2011
ISSN: 0891-6934,1607-842X
DOI: 10.3109/08916934.2011.606444